Formation of the MCC complex Authored: Yen, T, 2004-05-05 00:00:00 Pubmed11535616 Reactome Database ID Release 43141437 Reactome, http://www.reactome.org ReactomeREACT_36 Reviewed: Peters, JM, 2006-03-27 22:55:09 Upon release from the kinetochore, Mad2 associates with Cdc20, hBUBR1, and hBUB3 to form the Mitotic Checkpoint Complex (MCC). Assembly of this complex does not depend on kinetochores but this complex can only inhibit APC/C that has undergone mitotic modifications. hBUBR1:hBUB3:MAD2*:CDC20 complex