p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D ARPP19 and ENSA, activated by MASTL (GWL) mediated phosphorylation, bind and inhibit PP2A complexed with the regulatory subunit PPP2R2D (B55-delta). Inhibition of PP2A-PPP2R2D phosphatase activity allows mitotis entry and mainetance by preventing dephosphorylation of CDK1 mitotic targets (Mochida et al. 2010, Gharbi-Ayachi et al. 2010). Authored: Orlic-Milacic, M, 2012-09-04 Edited: Gillespie, ME, 2012-09-14 Pubmed21164013 Pubmed21164014 Reactome Database ID Release 432430552 Reactome, http://www.reactome.org ReactomeREACT_150301 Reviewed: Burgess, A, 2012-09-28 Reviewed: Mochida, Satoru, 2012-09-26 p-S62-ARPP19/p-S67-ENSA p-S62-ARPP19/p-S67-ENSA:PP2A-PPP2R2D PP2A-PPP2R2D