Inactivation of PDC by phosphorylation of PDC E1 alpha component PathwayStep2153 PathwayStep2152 'Acetyl-CoA [mitochondrial matrix]' positively regulates 'PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit' 'NADH [mitochondrial matrix]' positively regulates 'PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit' 'PYR [mitochondrial matrix]' negatively regulates 'PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit'