PathwayStep1696 PathwayStep1695 PathwayStep1697 PathwayStep1693 PathwayStep1694 PathwayStep1691 PathwayStep1692 PE is hydrolyzed to 2-acyl LPE by PLA2G4C PE is hydrolyzed to 2-acyl LPE by PLA2[4] PE is hydrolyzed to 1-acyl LPE by PLA2[16] 2-acyl LPE is acylated to PE by LPEAT PE is hydrolyzed to 1-acyl LPE by PLA2[2] 1-acyl LPE is acylated to PE by LPEAT PE is hydrolyzed to 1-acyl LPE by PLA2[3] Acyl chain remodelling of PE Authored: Williams, MG, 2011-09-14 Edited: Williams, MG, 2011-08-12 GENE ONTOLOGYGO:0036152 In the acyl chain remodelling pathway (Lands cycle), phosphatidylethanolamine (PE) is hydrolyzed by phopholipases and subsequently reacylated by acyltransferases. These cycles modify the fatty acid composition of glycerophospholipids to generate diverse molecules asymmetrically distributed in the cell membrane (Ghomashchi et al. 2010, Singer et al. 2002, Cao et al. 2008, Zhao et al. 2008, Hishikawa et al. 2008). Pubmed12359733 Pubmed18195019 Pubmed18287005 Pubmed18458083 Pubmed20705608 Reactome Database ID Release 431482839 Reactome, http://www.reactome.org ReactomeREACT_121369 Reviewed: Wakelam, Michael, 2012-05-14