urokinase plasminogen activator (one-chain):uPAR urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR Authored: D'Eustachio, P, 2005-02-14 18:06:15 Edited: D'Eustachio, P, 0000-00-00 00:00:00 Pubmed1846368 Pubmed2156852 Pubmed3023326 Reactome Database ID Release 43158959 Reactome, http://www.reactome.org ReactomeREACT_1386 The uncleaved (one-chain) form of urokinase plasminogen activator associates with urokinase plasminogen activator receptor (uPAR), forming a complex at the cell surface (Cubellis et al. 1986). The complex is anchored to the outer face of the plasma membrane by a glycophosphatidylinositol moiety at the carboxy terminus of uPAR (Behrendt et al. 1990; Ploug et al. 1991).