PathwayStep1785 PathwayStep1786 PG is converted to BMP PG transports from the ER membrane to the late endosome membrane Synthesis of BMP Authored: Williams, MG, 2011-09-14 Edited: Williams, MG, 2011-08-12 GENE ONTOLOGYGO:2001312 Lysobisphosphatidic acid, also known as bis(monoacylglycerol) hydrogen phosphate (BMP), is enriched in late endosomes and not found in the endoplasmic reticulum (ER) or mitochondria where phosphatidylglycerol (PG) is synthesized. Late endosomes form membrane contact sites with the ER, providing a means for PG to enter the late endosome and be converted to BMP via hydrolysis by a phospholipase A2, followed by acylation, and a reorientation of the phosphoryl ester (Poorthuis & Hostetler 1978, Heravi & Waite 1999, Hullin-Matsuda et al. 2007, Gallala & Sandhoff 2010). Pubmed10101262 Pubmed17558022 Pubmed21136156 Pubmed650089 Reactome Database ID Release 431483171 Reactome, http://www.reactome.org ReactomeREACT_121039