PathwayStep1337 PathwayStep1339 PathwayStep1338 L-methylmalonyl-CoA <=> succinyl-CoA D-methylmalonyl-CoA <=> L-methylmalonyl-CoA propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate Propionyl-CoA catabolism Authored: 2003-04-11 00:00:00 Edited: D'Eustachio, P, 0000-00-00 00:00:00 GENE ONTOLOGYGO:0019626 ISBN0079130356 Propionyl-CoA is a product of the catabolism of the amino acids, leucine, methionine, and threonine, and of the beta-oxidation of fatty acids with odd numbers of carbon atoms. The three reactions of this pathway convert propionyl-CoA to succinyl-CoA, an intermediate of the citric acid cycle. Through these reactions, carbon atoms from these sources can be fully oxidized to produce energy, or can be directed to gluconeogenesis. The three reactions of propionyl-CoA catabolism take place in the mitochondrial matrix. Reactome Database ID Release 4371032 Reactome, http://www.reactome.org ReactomeREACT_993