PathwayStep1299 PathwayStep1324 PathwayStep1328 PathwayStep1314 PathwayStep1319 PathwayStep1309 PathwayStep1304 Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of butanoyl-CoA to acetyl-CoA Beta oxidation of myristoyl-CoA to lauroyl-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA mitochondrial fatty acid beta-oxidation of saturated fatty acids Authored: Gillespie, ME, 2003-09-19 00:00:00 Edited: Gillespie, ME, 0000-00-00 00:00:00 ISBN0079130356 Once fatty acids have been imported into the mitochondrial matrix by the carnitine acyltransferases, the beta-oxidation spiral begins. Each turn of this spiral concludes with the repetitive removal of two carbon units from the fatty acyl chain. beta-oxidation of saturated fatty acids (fatty acids with even numbered carbon chains and no double bonds) involves four different enzymatic steps: oxidation, hydration, a second oxidation, and a concluding thiolysis step, resulting in the two-carbon acetyl-CoA and a newly CoA primed acyl-CoA for the next turn of the spiral. Reactome Database ID Release 4377286 Reactome, http://www.reactome.org ReactomeREACT_1541 Beta oxidation of palmitoyl-CoA to myristoyl-CoA