TFPI:TF:F7a:factor Xa factor Xa TF:F7a Inactivation of factor VIIa by TFPI Authored: D'Eustachio, P, 2004-08-24 14:00:00 Pubmed2271516 Reactome Database ID Release 43140825 Reactome, http://www.reactome.org ReactomeREACT_654 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa TFPI binds to the factor VIIa:TF complex and to factor Xa at the endothelial surface, forming a stable heterotetrameric complex in which factor VIIa is catalytically inactive.