GRB2 bound to pFADK1 in Focal adhesion SOS bound to Grb2:pFADK1 Interaction of SOS with GRB2 bound to FADK1 Authored: Garapati, P V, 2008-06-16 17:13:06 Edited: Garapati, P V, 2008-06-16 17:13:06 Pubmed7997267 Reactome Database ID Release 43354165 Reactome, http://www.reactome.org ReactomeREACT_15405 Reviewed: Shattil, SJ, 2008-09-16 06:21:39 Son of sevenless protein homolog 1(SOS) is an activating nucleotide exchange factor for H-Ras (p21Ras). SOS is brought close to the H-Ras by interacting with the FADK1 bound GRB2.