Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC) Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) Autophosphorylation of SRC Authored: Garapati, P V, 2008-06-16 17:13:06 Clustering of Integrin alphaIIb beta3 complexes results in the trans auto-phosphorylation of SRC tyrosine residue 419 (often referred to as 418 in the literature, as the initiating methionine is cleaved in the mature peptide) in SRC's kinase activation loop. EC Number: 2.7.10 Edited: Garapati, P V, 2008-06-16 17:13:06 Pubmed16005629 Reactome Database ID Release 43377640 Reactome, http://www.reactome.org ReactomeREACT_15545 Reviewed: Shattil, SJ, 2008-09-16 06:21:39 has a Stoichiometric coefficient of 2