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    <!-- http://purl.obolibrary.org/obo/INO_0000080 -->

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    <!-- http://purl.obolibrary.org/obo/HINO_0007082 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0007082">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Expression of Squalene Monooxygenase (SQLE)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0014275 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0014275">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">&#39;SREBP1A/2:SQLE gene [nucleoplasm]&#39; positively regulates &#39;Expression of Squalene Monooxygenase (SQLE)&#39;</rdfs:label>
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        <ns3:controlType rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ACTIVATION</ns3:controlType>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pubmed11485325</obo:IAO_0000119>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pubmed11994399</obo:IAO_0000119>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pubmed12083769</obo:IAO_0000119>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pubmed17027328</obo:IAO_0000119>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pubmed18654640</obo:IAO_0000119>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reactome Database ID Release 431655871</rdfs:seeAlso>
        <obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reactome, http://www.reactome.org</obo:IAO_0000119>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ReactomeREACT_148651</rdfs:seeAlso>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SREBF1A (SREBP1A) and SREBF2 (SREBP2) bind the promoter of the Squalene Monooxygenase (SQLE) gene and enhance transcription (Sakakura et al. 2001, Nagai et al. 2002,  Murphy et al. 2006, Reed et al. 2008, reviewed in Horton et al. 2002).</rdfs:comment>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0023055 -->

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        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SREBP1A/2:SQLE gene</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/INO_0000101 -->

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