GPIb-IX-V:vWF:14-3-3-zeta GPIb-IX-V:vWF:14-3-3-zeta:p85 GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K Authored: Akkerman, JW, 2009-09-04 Edited: Jupe, S, 2010-06-07 Pubmed10887121 Pubmed16102041 Reactome Database ID Release 43443402 Reactome, http://www.reactome.org ReactomeREACT_23952 Resting platelets contain a heterotrimeric complex of GPIb-IX-V, 14-3-3-zeta and the p85 subunit of PI-3K. While GPIb-IX-V has no apparent binding sites for PI3K so the interaction with p85 is likely to be mediated by 14-3-3-zeta. Reviewed: Kunapuli, SP, 2010-06-07