Biotin transport across the plasma membrane PathwayStep2362 Biotin metabolism Authored: Jassal, B, 2007-04-24 08:38:46 Biotin is an essential cofactor in a variety of carboxylation reactions. It is abundant in the human diet, and can be taken up from the intestinal lumen by the SLC5A6 transporter (Zempleni et al. 2009). Its covalent attachment to carboxylase enzymes is catalyzed by the HLCS enzyme in a reaction to be annotated in a future release of Reactome. GENE ONTOLOGYGO:0006768 Pubmed19319844 Reactome Database ID Release 43196780 Reactome, http://www.reactome.org ReactomeREACT_11153