Pyridoxamine is phosphorylated PLP results from phosphorylation of pyridoxal PLP from oxidation of pyridoxine phosphate PLP from oxidation of pyridoxamine phosphate Pyridoxine is phosphorylated PathwayStep2357 PathwayStep2358 PathwayStep2356 PathwayStep2359 PathwayStep2360 Vitamins B6 activation to pyridoxal phosphate Animals cannot synthesize pyridoxal 5'-phosphate (PLP) which is a ligand in aminotransferases and other enzymes. PLP's accessible derivatives pyridoxine, pyridoxal, and pyridoxamine are traditionally called vitamins B6. They are taken up nutritionally from bacteria and plants, but also created from PLP in the body. The pathways used to recycle PLP from these three compounds can therefore be called vitamin B6 activation as well as PLP salvage. Because of the close similarity of the molecules, only two enzymes are needed for the task (McCormick & Chen, 1999). Authored: Stephan, R, 2010-09-16 Edited: Jassal, B, 2010-09-20 GENE ONTOLOGYGO:0042816 Pubmed10024608 Reactome Database ID Release 43964975 Reactome, http://www.reactome.org ReactomeREACT_25012 Reviewed: D'Eustachio, P, 2010-11-08