LDL LDL:LRP8 LDL binds to LRP8 Authored: Akkerman, JW, 2009-09-04 Edited: Jupe, S, 2010-06-07 LPR8 (apoER2) is the platelet low density lipoprotein (LDL) receptor. Mice lacking ApoE develop hypercholesterolemia and later atherosclerosis (Zhang et al. 1992). Similiar results are seen in familial hypercholesterolemia, where defective apoB/E receptors fail to remove LDL from the circulation. Pubmed1411543 Pubmed15459198 Reactome Database ID Release 43432121 Reactome, http://www.reactome.org ReactomeREACT_23972 Reviewed: Kunapuli, SP, 2010-06-07