Expression of BMAL1 (ARNTL). Authored: May, B, 2009-05-17 22:04:50 Edited: May, B, 2009-06-02 00:51:49 Pubmed9079689 Pubmed9144434 Reactome Database ID Release 43400342 Reactome, http://www.reactome.org ReactomeREACT_25233 Reviewed: Albrecht, U, 2010-06-23 Reviewed: D'Eustachio, P, 2009-05-26 22:13:22 Reviewed: Delaunay, F, 2010-06-23 Reviewed: Hirota, T, 2010-06-23 Reviewed: Kay, SA, 2010-06-23 The BMAL1 (ARNTL) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. The ROR-alpha transcription factor binds the RORE element of the BMAL1 (ARNTL) promoter and activates transcription of the BMAL1 gene. The REV-ERBA transcription factor binds the same RORE element and represses transcription of the BMAL1 gene.