HNF6-dependent synthesis of ONECUT3 protein during morphogenesis Authored: Ferrer, J, Tello-Ruiz, MK, 2008--0-5- Edited: D'Eustachio, P, 2008-05-12 21:43:33 Reactome Database ID Release 43210837 Reactome, http://www.reactome.org ReactomeREACT_13722 Reviewed: Jensen, J, 2008-05-12 21:46:53 The ONECUT3 gene is transcribed, its mRNA is translated, and the protein product is transported to the nucleus during morphogenesis of the pancreas. ONECUT3 transcription requires the activity of the HNF6 transcription factor. These events and interactions have not been studied directly in humans, but are inferred from corresponding ones worked out in the mouse.