HNF1A-dependent synthesis of FOXA3 Authored: Ferrer, J, Tello-Ruiz, MK, 2008--0-5- Edited: D'Eustachio, P, 2008-05-12 21:43:33 Pubmed11717395 Reactome Database ID Release 43211482 Reactome, http://www.reactome.org ReactomeREACT_13553 Reviewed: Jensen, J, 2008-05-12 21:46:53 The FOXA3 gene is transcribed, its mRNA is translated, and the protein product is localized to the nucleoplasm. FOXA3 expression is positively regulated by HNF1A. The molecular details of FOXA3 expression in intact pancreatic beta cells have not been studied in humans, but are inferred from corresponding ones worked out in the mouse (Boj et al. 2001).