43S complex mRNA:eIF4F:eIF4B:eIF4H 43S:mRNA:eIF4F:eIF4B:eIF4H Formation of translation initiation complexes containing mRNA that does not circularize Pubmed592399 Pubmed641056 Pubmed6853548 Pubmed9732867 Reactome Database ID Release 43157849 Reactome, http://www.reactome.org ReactomeREACT_1904 The translation initiation complex forms when the 43S complex binds the mRNA that is associated with eIF4F, eIF4B and eIF4H. eIF4G in the eIF4F complex can directly contact eIF3 in the 43S complex. eIF1A is necessary for the formation of this complex.