Spliceosomal m3G capped snRNA:SMN:SM:Snurportin complex Spliceosomal m3G capped snRNAs with SMN:SM protein complex bound snRNP:Snurportin complex formation Authored: Gillespie, ME, 2007-01-29 20:29:54 GENE ONTOLOGYGO:0000387 Pubmed12095920 Pubmed12776181 Pubmed9670026 Reactome Database ID Release 43191763 Reactome, http://www.reactome.org ReactomeREACT_9946 Reviewed: Luhrmann, R, 2007-04-30 18:31:22 The nuclear import signal has two parts; Cap hypermethylation triggers nuclear import via snurportin1 binding and by receptor recognition of the Sm proteins. Snurportin1 (SPN) is an adaptor that links the assembled snRNP to the nuclear transport machinery, recruiting importin beta for nuclear import. The import receptor that recognizes the Sm proteins is not yet known.