MCM8 ORC complex bound to origin ORC:origin Association of MCM8 with ORC:origin complex Authored: Tye, BK, 2006-03-17 14:46:24 Edited: Gopinathrao, G, 2006-03-17 14:47:28 Pubmed15684404 Reactome Database ID Release 43176973 Reactome, http://www.reactome.org ReactomeREACT_6731 The MCM2-7 complex, an essential component of the pre-replication complex, recruits CDC6 and CDT1 proteins to the origin. MCM8, another member of the MCM family has been found to bind to chromatin during early G1 phase. MCM8 interacts specifically with the ORC2 protein.