Replication Fork Unwinding complex at replication fork GINS complex Mcm2-7 complex Multiple proteins are localized at replication fork Authored: Tye, BK, 2006-03-17 14:46:24 By applying the chromatin immunoprecipitation technique to paused forks, certain proteins like DNA pol alpha, DNA pol delta, DNA pol epsilon, MCM2-7, CDC45, GINS and MCM10 were identified. By uncoupling a helicase at the site using a polymerase inhibitor, MCM2-7, GINS complex and CDC45 alone were found to be enriched at the paused fork suggesting these proteins may form a part of an "unwindosome" at the replicating fork. Edited: Gopinathrao, G, 2006-03-17 14:47:28 Pubmed16483939 Reactome Database ID Release 43176942 Reactome, http://www.reactome.org ReactomeREACT_6963