SARA TGFB1:TGFBR2:TGFBR1 GADD34:PP1CC TGFB1:p-TGFBR:Smad7:GADD34:PP1CC:SARA PP1CC dephosphorylates TGFBR1 Authored: Heldin, CH, Moustakas, A, Huminiecki, L, Jassal, B, 2006-02-02 EC Number: 3.1.3.16 Edited: Jassal, B, 2012-04-10 Phosphorylated TGFBR1 is significantly dephosphorylated when incubated with Smad7, PPP1R15A (GADD34) and PP1CC, immunoprecipitated from previously transfected COS1 cells. Dephosphorylation is inhibited by addition of PP1 inhibitor I-1 (Shi et al. 2004). Pubmed14718519 Reactome Database ID Release 432167872 Reactome, http://www.reactome.org ReactomeREACT_120899 Reviewed: Huang, Tao, 2012-05-14 has a Stoichiometric coefficient of 6