SPRY2 is serine phosphorylated in response to MAPK activation 'p-ERK dimer [cytosol]' is required for 'SPRY2 is serine phosphorylated in response to MAPK activation' ACTIVATION Phosphorylation of serine residues 111 and 120 on SPRY2 requires MAPK activation, however the identity of the phosphorylating kinase has not been established. Pubmed11698404 Pubmed19690147 Reactome Database ID Release 431295627 Reactome, http://www.reactome.org ReactomeREACT_111903 p-ERK dimer