PathwayStep842 PathwayStep841 PathwayStep844 PathwayStep843 PathwayStep846 PathwayStep845 PathwayStep840 PathwayStep838 PathwayStep839 PathwayStep837 PathwayStep836 PathwayStep835 PathwayStep834 PathwayStep833 Kinesins Authored: Akkerman, JW, 2010-10-29 Edited: Jupe, S, 2010-11-15 GENE ONTOLOGYGO:0007018 Kinesins are a superfamily of microtubule-based motor proteins that have diverse functions in transport of vesicles, organelles and chromosomes, and regulate microtubule dynamics. There are 14 families of kinesins, all reprsented in humans. A standardized nomenclature was published in 2004 (Lawrence et al.). Pubmed15479732 Pubmed18626067 Pubmed19851335 Pubmed20930137 Reactome Database ID Release 43983189 Reactome, http://www.reactome.org ReactomeREACT_25201 Reviewed: Ouwehand, WH, 2010-11-12 Kinesin-1 is a heterotetramer Kinesin-14 is a dimer Kinesins move along microtubules consuming ATP Kinesins bind microtubules Kinesin-9 is a dimer Kinesin-8 is a dimer Kinesin-7 is a dimer Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin Kinesin-13 is a dimer Kinesin-12 is a dimer Kinesin-5 is a homotetramer Chromokinesins form dimers Kinesin-3 is a dimer Kinesin-2 is a heterotrimer