Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex AUF1 Complexed with Translation and Heat Shock Proteins Ubiquitination of AUF1 (hnRNP D0) AUF1 is ubiquitinated at unknown sites. The number of ubiquitin molecules conjugated to AUF1 and their linkage is unknown. Ubiquitination is required for subsequent degradation of both AUF1 and the mRNA bound by AUF1. It is uncertain if AUF1 is in a larger complex when it is ubiquitinated. Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29 Pubmed10205060 Pubmed10559216 Pubmed11842200 Pubmed12136087 Reactome Database ID Release 43450580 Reactome, http://www.reactome.org ReactomeREACT_25315 Reviewed: Wilusz, J, 2010-06-29 has a Stoichiometric coefficient of 4 ubiquitin