ERKs are inactivated ERK/MAPK targets Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 ERK/MAPK kinases have a number of targets within the nucleus, usually transcription factors or other kinases. The best known targets, ELK1, ETS1, ATF2, MITF, MAPKAPK2, MSK1, RSK1/2/3 and MEF2 are annotated here. Reactome Database ID Release 43198753 Reactome, http://www.reactome.org ReactomeREACT_12599 Reviewed: Greene, LA, 2007-11-08 15:39:37 PathwayStep3464 PathwayStep3465 PathwayStep3471 PathwayStep3467 PathwayStep3466 PathwayStep3469 PathwayStep3468 ERKs are inactivated by protein phosphatase 2A ERK5 activates the transcription factor MEF2 ERK1/2/5 activate RSK1/2/3 p38MAPK phosphorylates MSK1 ERK1/2 phosphorylates MSK1 ERK1/2 activates ELK1