RNA Pol II (hypophosphorylated):capped pre-mRNA complex RNA Pol II (hypophosphorylated) complex bound to DSIF protein DSIF complex DSIF complex binds to RNA Pol II (hypophosphorylated) Authored: Gopinathrao, G, 2004-05-03 18:16:42 DSIF is a heterodimer consisting of hSPT4 (human homolog of yeast Spt4- p14) and hSPT5 (human homolog of yeast Spt5-p160). DSIF association with Pol II may be enabled by Spt5 binding to Pol II creating a scaffold for NELF binding (Wada et al.,1998). Spt5 subunit of DSIF can be phosphorylated by P-TEFb. Pubmed12653964 Pubmed9450929 Reactome Database ID Release 43113407 Reactome, http://www.reactome.org ReactomeREACT_802