PathwayStep4081 PathwayStep4082 FGFR1c binds to FGF Autocatalytic phosphorylation of FGFR1c FGFR1c ligand binding and activation Authored: de Bono, B, 2007-01-10 10:27:18 GENE ONTOLOGYGO:0008543 Pubmed16597617 Reactome Database ID Release 43190373 Reactome, http://www.reactome.org ReactomeREACT_9515 Reviewed: Mohammadi, M, 2007-02-06 21:44:35 This pathway depicts the binding of an experimentally-verified range of ligands to FGFR1c. While binding affinities may vary considerably within this set, the ligands listed have been established to bring about receptor activation at their reported physiological concentrations.