PathwayStep2571 PathwayStep2570 PathwayStep2568 PathwayStep2569 Glycoprotein hormones Authored: Jassal, B, 2008-10-01 13:18:42 Edited: Jassal, B, 2008-11-17 10:09:58 More complex protein hormones have carbohydrate side chains and are called glycoprotein hormones. Hormones in this class are Follicle-stimulating hormone (FSH; follitropin), Luteinizing hormone (LH), Thyroid-stimulating hormone (TSH; thyrotropin) and human chorionic gonadotropin (hCG). The alpha subunit of glycoprotein hormones is a 92 aa peptide and serves as the alpha subunit for FSH, LH, hCG and TSH (Fiddes JC and Goodman HM, 1981). The beta subunits for these hormones are unique and confer biological specificity to them. These two subunits combine via disulphide bonding to produce the mature glycoprotein hormone dimer. Pubmed6267989 Pubmed6286817 Reactome Database ID Release 43209822 Reactome, http://www.reactome.org ReactomeREACT_15398 Reviewed: D'Eustachio, P, 2008-11-29 15:53:45 Luteinizing hormone is a heterodimer Human chorionic gonadotropin (hCG) is a heterodimer Thyrotropin is a heterodimer Follitropin is a heterodimer