PathwayStep2750 PathwayStep2747 PathwayStep2753 Conjugation of benzoate with glycine Conjugation of phenylacetate with glutamine Conjugation of carboxylic acids Authored: Jassal, B, 2005-03-10 15:37:26 Edited: Jassal, B, 2008-05-19 12:57:01 GENE ONTOLOGYGO:0006805 Reactome Database ID Release 43159424 Reactome, http://www.reactome.org ReactomeREACT_6889 Xenobiotics and endogenous compounds containing carboxylate groups can be activated with coenzyme A to produce acyl-CoA thioesters and then conjugated with the amino groups of glycine or glutamine to form amide-linked conjugates. Clinically important substrates include benzoic acid, phenylacetic acid, and salicylic acid. Conjugation of salicylate with glycine