PathwayStep2782 PathwayStep2781 PathwayStep2780 Abacavir transmembrane transport Authored: D'Eustachio, P, 2012-03-14 Cytosolic levels of abacavir are determined by the balance of its facilitated diffusion into the cell mediated by organic cation transporters SLC22A1, 2, and 3, and its ATP-dependent efflux from cells mediated by ABCG2 and ABCB1 (Klaasen and Aleksunes 2010; Pan et al. 2007; Shaik et al. 2007). Edited: D'Eustachio, P, 2012-03-16 GENE ONTOLOGYGO:0006855 Pubmed17437964 Pubmed17709369 Pubmed20103563 Reactome Database ID Release 432161517 Reactome, http://www.reactome.org ReactomeREACT_120801 Reviewed: Jassal, B, 2012-03-16 abacavir [extracellular] => abacavir [cytosol] ABCG2-mediated abacavir efflux ABCB1-mediated abacavir efflux