PathwayStep2926 PathwayStep2927 PathwayStep2924 PathwayStep2925 ATM mediated phosphorylation of repair proteins Authored: Matthews, L, 2003-11-18 00:00:00 Following the detection of DSBs, ATM mediates the phosphorylation of proteins involved in DNA repair (Thompson and Schild, 2002). Pubmed12427531 Reactome Database ID Release 4375148 Reactome, http://www.reactome.org ReactomeREACT_1924 Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB Phosphorylation of BRCA1 at multiple sites by ATM Phosphorylation of NBS1 by ATM Phosphorylation of MDC1/NFBD1 by ATM (within 2 c-term BRCT domains)