PathwayStep2946 PathwayStep2947 PathwayStep2944 PathwayStep2945 PathwayStep2951 Assembly of the RAD51-ssDNA nucleoprotein complex Presynaptic phase of homologous DNA pairing and strand exchange Reactome Database ID Release 4376003 Reactome, http://www.reactome.org ReactomeREACT_408 The presynaptic phase of homologous DNA pairing and strand exchange begins with the displacement of RPA from ssDNA, followed by the association of RAD51 with BRCA2, formation of RAD52 heptameric ring structure complexes on ssDNA, association of RAD52 with the RPA complex, association of RAD52 with ssDNA at resected ends of double-strand break and assembly of the RAD51-ssDNA nucleoprotein complex. Association of RAD51 with BRCA2 Association of RAD52 with ssDNA at resected ends of double-strand break Association of RAD52 with the RPA complex Formation of RAD52 heptameric ring structure complexes on ssDNA