Folding of actin by CCT/TriC Authored: Matthews, L, 2008-12-01 04:46:41 Edited: Matthews, L, 2009-02-21 04:38:35 GENE ONTOLOGYGO:0051086 Nucleotide-independent transfer of beta-actin from prefoldin to CCT occurs when prefoldin binds to CCT (Vainberg et al., 1998). Following ATP- dependent folding within CCT (Gao et al., 1992), beta-actin is released as a soluble, monomeric protein. Pubmed1351421 Pubmed8104191 Pubmed9630229 Reactome Database ID Release 43390450 Reactome, http://www.reactome.org ReactomeREACT_17050 Reviewed: Cowan, NJ, 2009-01-21 16:47:24 PathwayStep3026 PathwayStep3025 Hydrolysis of ATP and release of folded actin from CCT/TriC Exchange of ADP for ATP in CCT/TriC:actin complex