PathwayStep874 Reuptake of GABA Authored: Mahajan, SS, 2010-08-02 Edited: Mahajan, SS, 2010-06-29 Pubmed19924586 Reactome Database ID Release 43888593 Reactome, http://www.reactome.org ReactomeREACT_23910 Reuptake of GABA from the synapse terminates the action of GABA thus regulating GABA action. GABA taken up from the synapse into the neurons is reused for synaptic loading. GABA taken up by astrocytes is degraded into C02 and glutamine. Glutamine is transported into the neurons for glutamate and GABA synthesis. Reviewed: Restituito, S, 2008-11-27 12:38:49 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine PathwayStep3272 GAT1-3 mediate Na+/Cl- dependent GABA transport