Acetylcholine Binding And Downstream Events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Authored: Mahajan, SS, 2008-01-14 16:01:52 Reactome Database ID Release 43112314 Reactome, http://www.reactome.org ReactomeREACT_15370 Reviewed: Restituito, S, Kavalali, E, 2008-12-02 04:33:19 The neurotransmitter in the synaptic cleft released by the pre-synaptic neuron binds specific receptors located on the post-synaptic terminal. These receptors are either ion channels or G protein coupled receptors that function to transmit the signals from the post-synaptic membrane to the cell body. Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Activation of NMDA receptor upon glutamate binding and postsynaptic events GABA receptor activation Activation of Kainate Receptors upon glutamate binding PathwayStep3309 PathwayStep3322 PathwayStep3382 PathwayStep3365 PathwayStep3354