Neurotransmitter Clearance In The Synaptic Cleft Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Neurotransmitter uptake and Metabolism In Glial Cells Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Neurotransmitter Release Cycle Transmission across Chemical Synapses Authored: Mahajan, SS, 2008-01-14 16:01:52 Chemical synapses are specialized junctions that are used for communication between neurons, neurons and muscle or gland cells. The synapse involves a pre-synaptic neuron and a post-synaptic neuron, muscle cell or glad cell. The pre and the post-synaptic cell are separated by a gap of 20nm called the synaptic cleft. The signals pass in a unidirection from pre-synaptic to post-synaptic. The pre-synaptic neuron communicates via the release of neurotransmitter which bind the receptors on the post-synaptic cell. Edited: Mahajan, SS, 2008-01-14 16:01:52 GENE ONTOLOGYGO:0007268 Reactome Database ID Release 43112315 Reactome, http://www.reactome.org ReactomeREACT_13477 Reviewed: Restituito, S, Kavalali, E, 2008-12-02 04:33:19 PathwayStep3278 PathwayStep3292 PathwayStep3296 PathwayStep3237 PathwayStep3383