14-3-3 dimer Phospho AS160:IRAP Phospho AS160:14-3-3:IRAP 14-3-3 Binds Phosphorylated AS160 (TBC1D4) AS160 (TBC1D4) phosphorylated on serines 318, 341, 570, 588, and 751 and threonine 642 binds to all 14-3-3 proteins, although binding to 14-3-3 delta is comparatively low (Ramm et al. 2006, Howlett et al. 2007, Ngo et al. 2009, Treebak et al. 2009, Koumanov et al. 2011). As inferred from mouse, binding to 14-3-3 does not interfere with the interaction between AS160 and IRAP (LNPEP). Authored: May, B, 2011-07-07 Edited: May, B, 2011-07-07 Pubmed16880201 Pubmed17369524 Pubmed19013499 Pubmed19252894 Pubmed21454690 Reactome Database ID Release 431445149 Reactome, http://www.reactome.org ReactomeREACT_147698 Reviewed: Klip, Amira, 2012-08-21