RAB4A:GTP:KIF3:microtubule RAB4A:GTP KIF3 microtubule RAB4A:GTP Activates KIF3 As inferred from mouse adipocytes, insulin signals via PKC-lambda to cause Rab4 to load GTP and associate with Kif3, which then has higher affinity for microtubules. Motor activity of Kif3 along microtubules is believed to transport vesicles containing Glut4 across the cytosol to the cortical actin network. Authored: May, B, 2012-05-27 Edited: May, B, 2012-05-27 Reactome Database ID Release 432316347 Reactome, http://www.reactome.org ReactomeREACT_147824 Reviewed: Klip, Amira, 2012-08-21