RAB8A/10/13/14:GTP RAB8A/10/13/14:GDP RAB8A/10/13/14 Exchange GDP for GTP Authored: May, B, 2012-05-16 Edited: May, B, 2012-05-16 Pubmed20631154 Pubmed20937701 RAB8A/10/13/14 release GDP and bind GTP to yield the active complex. Guanine nucleotide exchange factors (GEFs) stimulate the reaction. GTPase-activating proteins (GAPs) oppose the reaction by stimulating the intrinsic GTPase activity of the RAB proteins. Reactome Database ID Release 432255343 Reactome, http://www.reactome.org ReactomeREACT_147746 Reviewed: Klip, Amira, 2012-08-21