Golgi-associated Vesicle Destined Cargo Vamp Golgi-associated Vesicle Destined Cargo AP-1 Complex Arf1-GTP Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture Authored: Gillespie, ME, 2009-08-27 Edited: Gillespie, ME, 2008-05-21 20:31:35 Once AP-1 is recruited to the trans-Golgi Network membrane the complex of functional vesicle building proteins is joined by the cargo that will be within that vesicle. As with other types of vesicles the cargo itself is part of the vesicle development. Here the cargo is destined for the Golgi-associated vesicle membrane. It is at this stage that a specific Synaptobrevin (Vamp) molecule also joins the complex. It should be noted that only certain Vamp molecules will be found with specific cargo molecules on the newly forming vesicles. However here we represent this reaction in bulk, without specific Vamp and cargo molecule pairings. Pubmed11694590 Pubmed11994746 Pubmed17116749 Reactome Database ID Release 43421833 Reactome, http://www.reactome.org ReactomeREACT_19391 Reviewed: Simpson, JC, 2009-08-27