Trans neurofascin dimer:ankyrin-G NFASC:pNFASC Phosphorylation of Neurofascin Authored: Garapati, P V, 2008-07-30 10:22:58 EC Number: 2.7.10 Edited: Garapati, P V, 2008-07-30 10:22:58 Reactome Database ID Release 43445091 Reactome, http://www.reactome.org ReactomeREACT_22202 Reviewed: Maness, PF, 2010-02-16 The highly conserved FIGQY motif in the cytoplasmic domain of neurofascin is phosphorylated by tyrosine kinases in response to external signals. Phosphorylation of the tyrosine in the FIGQY motif inhibits ankyrin binding.