FoxO3a-binding Element SMAD2/3:SMAD4:FOXO3:FoxO3a-binding Element p-2S-SMAD2/3:SMAD4 Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 Binds FoxO3a-binding Elements Authored: May, B, 2011-08-26 Edited: May, B, 2011-08-26 FOXO3 (FOXO3A) interacts with phospho-SMAD2 and phospho-SMAD3 complexed with CO-SMAD (SMAD4) at a promoter containing the FoxO3a-binding Element (Fu and Peng 20110). Pubmed21532621 Reactome Database ID Release 431535903 Reactome, http://www.reactome.org ReactomeREACT_111216 Reviewed: Peng, C, 2011-08-24