<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/HINO?iri=http://purl.obolibrary.org/obo/HINO_0017414"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0002233 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002233"/>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002234 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002234"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/HINO_0003668 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0003668">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LEFTY</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0008313 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0008313">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LEFTY:EGF-CFC:NODAL Receptor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0008361 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0008361">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NODAL Receptor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0017414 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0017414">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LEFTY Binds the EGF-CFC Coreceptor in the NODAL Receptor</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/INO_0000040"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HINO_0008361"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002234"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HINO_0008313"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HINO_0003668"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Authored: May, B, 2011-01-27</rdfs:comment>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Edited: May, B, 2011-01-27</rdfs:comment>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LEFTY1 and LEFTY2 are able to inhibit NODAL signaling by binding the EGF-CFC coreceptor (CRIPTO or CRYPTIC) and thereby preventing the coreceptor from interacting with other components of the NODAL receptor.</rdfs:comment>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reactome Database ID Release 431181351</rdfs:seeAlso>
        <ns3:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reactome, http://www.reactome.org</ns3:IAO_0000119>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ReactomeREACT_111240</rdfs:seeAlso>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reviewed: Peng, C, 2011-08-24</rdfs:comment>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/INO_0000040 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/INO_0000040"/>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



