Smad7:SMURF1 Smad7:SMURF1 complex binds XPO1 (CRM1) Authored: Orlic-Milacic, M, 2012-04-04 Edited: Jassal, B, 2012-04-10 Pubmed12519765 Reactome Database ID Release 432169012 Reactome, http://www.reactome.org ReactomeREACT_121131 Reviewed: Huang, Tao, 2012-05-14 Smad7:SMURF1 complex, formed by exogenous expression of recombinant human SMURF1 and recombinant mouse Smad7 in COS7 cells, binds to XPO1 (CRM1). Recombinant XPO1 was also exogenously expressed in COS7 cells, and since the species origin of XPO1 is not specified in the paper by Tajima et al., it is assumed that XPO1 is of human origin (Tajima et al. 2003). Smad7:SMURF1:XPO1