Coatomer:GAP Lattice Coatomer:GAP Lattice Sculpting and pinching-off of Golgi vessicle All of the key components and regulators of the COPI coat (GBF1, Arf1, ArfGAP1 and coatomer) cycle on and off the Golgi membrane. This cycle is required for vesicle formation, but is uncoupled from the actual vesicle release. Continuous membrane binding and release of these molecules enables the COPI lattice to be dynamically modulated. Once the vesicle is released from the Golgi apparatus, this lattice is completely disassociated from the vesicle. Authored: Gillespie, ME, 2007-07-23 15:44:13 Pubmed12379802 Pubmed14654841 Reactome Database ID Release 43200516 Reactome, http://www.reactome.org ReactomeREACT_11138 Reviewed: Rush, MG, 2008-01-11 00:00:00