PathwayStep4645 PathwayStep4654 PathwayStep4659 Kinetochore capture of astral microtubules Mitotic Prometaphase GENE ONTOLOGYGO:0000236 Reactome Database ID Release 4368877 Reactome, http://www.reactome.org ReactomeREACT_682 The dissolution of the nuclear membrane marks the beginning of the prometaphase. Kinetochores are created when proteins attach to the centromeres. Microtubules then attach at the kinetochores, and the chromosomes begin to move to the metaphase plate. Resolution of Sister Chromatid Cohesion Condensation of Prometaphase Chromosomes