PathwayStep4796 PathwayStep4798 PathwayStep4799 PARVB/Affixin interacts with alpha PIX Rsu-1 interacts with Pinch1 Association of PARVA with TESK1 PARVB interacts with Alpha-actinin PARVA associates with Paxillin PathwayStep4800 PathwayStep4801 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components Authored: Matthews, L, 2009-10-12 Edited: Matthews, L, 2009-11-10 Pubmed15246679 Reactome Database ID Release 43446388 Reactome, http://www.reactome.org ReactomeREACT_20580 Reviewed: Wu, C, 2009-11-12 The PINCH–ILK–Parvin complexes function in transducing diverse signals from ECM to intracellular effectors. Interacting partners for components of these complexes have been identified, a number of which regulate and/or mediate its functions in cytoskeletal remodeling and cell spreading (reviewed in Wu, 2004).